WebFeb 20, 2024 · Two evolutionarily conserved tethering complexes, homotypic fusion and protein sorting (HOPS) and class C core vacuole/endosome tethering (CORVET), are involved in … WebMay 3, 2024 · Levels of other HOPS/CORVET subunits, including VPS33A, were similarly reduced, but restored upon re-expression of VPS16. Patient-derived fibroblasts showed defects in the uptake and endosomal trafficking of transferrin as well as accumulation of autophagosomes and lysosomal compartments. Re-expression of VPS16 rescued the …
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WebJan 8, 2024 · VPS11 VPS11 core subunit of CORVET and HOPS complexes [ Homo sapiens (human) ] Gene ID: 55823, updated on 6-Nov-2024 Download Datasets Summary Official Symbol VPS11 provided by HGNC Official Full Name VPS11 core subunit of CORVET and HOPS complexes provided by HGNC Primary source … WebDec 18, 2015 · Mammalian CORVET and HOPS subunits significantly differ from their yeast homologues, and novel proteins with high homology to CORVET/HOPS subunits have … loonier than a
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